Abstract: The establishment of piano curriculum group of musicology major in the application-oriented university should integrate piano teaching objectives of knowledge, ability and quality from teaching content system, curriculum structure system, ability goal system and quality guarantee system. Piano curriculum group is established with application as the goal, harmony as the core, integration as the premise, piano as the method. The students performance and creativity ability is constantly upgraded by increasing the challenge of the curriculum, which achieves the cultivating goal of application-oriented, skill-oriented, innovation and compound music talents.