Abstract: Based on the current situation and characteristics of manufacturing enterprises in Anhui Province, this paper analyzes the connotation of management efficiency and its effect on the enterprises' development, constructs a comprehensive index evaluation system of manufacturing industry's management efficiency, and adopts the method of super-efficiency data envelopment analysis to rank and compare the management efficiency of 10 listed manufacturing enterprises in Anhui Province. Results show that manufacturing enterprises should not only pay attention to economic benefits, but also to social responsibility and adhere to independent innovation.