Abstract: Internet plus can give new opportunities to the development of traditional industries. In the era of internet plus, the fusion path of Anhui's Chinese medicine industry development includes the establishment of internet based dynamic monitoring information system for Chinese medicine resources, the development of Chinese medicine industry by using Internet of things, the analysis of big data of traditional Chinese medicine and artificial intelligence of Chinese medicine. The development mode of Internet plus in Anhui's Chinese medicine industry includes product mode, business mode and circulation channel mode.