Abstract: In order to deepen the reform of entrepreneurship and innovation education in colleges and universities, academic attributes are expanded and professional attributes and general attributes are integrated in professional education, so as to promote the integration of entrepreneurship education and professional education, which improves the professional level and effect of innovation and entrepreneurship. The cultivation of innovation and entrepreneurship quality is the core of entrepreneurship education. To strengthen the integration of entrepreneurship education and professional education, it is necessary to strengthen and plan the integration, develop the integration in curriculum, teachers, evaluation and other aspects, and effectively expand the integration methods and ways, so as to improve the quality of talent training.