Abstract: Promoting the high-end transformation of manufacturing is an important task for China to construct a powerful manufacturing. Under the background of global industrial reform and “reindustrialization” in developed countries, the high-end development of China’s manufacturing faces many challenges, so we need to rapidly improve the manufacturing innovation system, strengthen the transformation of quality, efficiency and power in manufacturing, accelerate the upgrading of new industries and transform traditional industries, deepen the development of “internet plus advanced manufacturing”, and promote the high-end manufacturing “going out” to enhance the international influence of “made in China”. Meanwhile, we need to learn from the advanced experience of developed countries to speed up the high-end process of China’s manufacturing.