Abstract: The existing issues in the teaching process of physical chemistry experiments, such as insufficient cultivation of students’ ability, low learning initiative and single evaluation system etc., propose a series of innovative reform strategies guided by the Outcome-Based Education (OBE) philosophy. These strategies include the precise construction of teaching objectives, the renewal and expansion of course content, the innovation of blended teaching models, the optimization of assessment systems, and the integration of ideological and political education into the teaching process. The formulation of specific reform measures are dedicated to establishing a student-centered, proactive learning-driven teaching system that enhances students’ capacity building.