Abstract: The transformation and innovation of the discourse of ideological and political education in colleges and universities in the digital era requires educators to capture the needs of young college students in the process of education with the thinking mode of cooperation and game, and realize the discourse transformation from “one-way” to “two-way”, “spoon-feeding” to “immersion”, “virtualization” to “combination of virtuality and reality”. Introduce the top-level design and practice strategy of the “post-truth” field in the five dimensions of theory, context, subject, practice and media, reconstruct the discourse of ideological and political education in colleges and universities, create a comprehensive and supporting education practice model of “online + offline”, dominate the “commanding heights” of online education in the digital era, and innovate and develop the discourse system of ideological and political education in colleges and universities in the digital era. Ensure the effectiveness of ideological and political education.