Abstract: The computer-aided design and manufacturing course provides classified teaching for students with different learning time and internship requirements, stimulating students' interest in learning and innovative practical abilities. To construct the teaching system of "three modes, two integrations and one management" for computer aided design and manufacturing course, explore multi-mode teaching schemes, and realize a diversified teaching system, which has achieved remarkable results in cultivating students' engineering awareness, safety awareness, quality awareness, management awareness, and so on, providing an effective guarantee for the construction of "new engineering" .