Abstract: General Secretary Xi Jinping's important discourse on comprehensively deepening reform is guided by the scientific principles of Marxist historical materialism, representing a profound summary of the Party's century-long historical experience and a vivid practice in Xi Jinping's political career. It embodies profound theoretical, cultural, historical, and practical logic. The core essence of General Secretary Xi Jinping's discourse on comprehensively deepening reform includes upholding the Party's overall leadership, adhering to a people-centered approach, maintaining the principle of upholding truth while innovating, focusing on institutional development as the main thread, adhering to comprehensive rule of law, and upholding a systemic perspective. In the new era and on the new journey, we must persist in comprehensively deepening reform, advance the great rejuvenation of the Chinese nation through the Chinese path to modernization, and provide Chinese solutions to global governance challenges.