Abstract: To deepen the teaching reform of basic courses and unify inter-university teaching evaluation standards, five universities of the Yangtze River Delta Higher Engineering Education Alliance have launched the joint examination of Advanced Mathematics since 2020. Taking this joint examination as an opportunity, Anhui University of Technology has continuously promoted the quality improvement of Advanced Mathematics teaching. At present, the Advanced Mathematics teaching faces prominent problems such as rigid traditional teaching modes, students' passive learning attitude, and the imbalance between the first classroom and the second classroom. This paper proposes optimization strategies from the perspectives of teaching innovation and learning methods. By integrating curriculum ideology and politics, adopting diversified teaching methods, optimizing intelligent teaching modes and digital evaluation systems, and constructing students' closed-loop autonomous learning mode, the overall teaching quality can be comprehensively improved.