Abstract: Entrepreneurship education in Anhui Undergraduate Colleges and Universities focuses on the comprehensive, systematic, targeted and effective nature of education.However, there are some problems such as lack of construction of curriculum system, teachers and linkage mechanism of entrepreneurial practice.Colleges and universities should deepen the reform of innovation and entrepreneurship education, strengthen the construction of the teacher team of entrepreneurial education, and improve entrepreneurial environment in order to further improve the effectiveness of entrepreneurship education.