Abstract: Internet plays an increasingly significant role in cross-cultural communication in the information age. Currently, the cross-cultural communication of Huangmei Opera is not optimistic because of several existing problems such as lack of online resources, low quality of web design, difficulties in content translation and so on. Therefore, it is necessary to strengthen the self-development of Huangmei Opera, improve the web design and carry out appropriate translation strategies, so as to ameliorate the Internet communication effect of Huangmei Opera' cross-cultural communication.