Abstract: The core essence of the Party’s ideological and theoretical dissemination is to realize the popularization, popularization and massification of theories, and to seek “effective supply”. Differences in the knowledge level, social class, regional characteristics, customs and habits of the general public will inevitably affect the depth, breadth and effectiveness of dissemination. In the context of new media, the dissemination and popularization of Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era must focus on the thinking of segmentation. The credibility, dissemination, influence and guidance of Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era will be continuously enhanced, through the segmentation strategies of promotion, products, recipients and channels.