Abstract: Communist Manifesto is a classic work that systematically expounds scientific socialism, and it is also a classic case of ideological and political education. Based on historical materialism, it systematically expounds the theoretical position of historical materialism, the political position of the proletariat, and the value position of communism, defines the content, principles, methods of ideological and political education of the proletariat,and showcases a unique expression technique. Based on the fundamental position and practical needs of Marxist ideological and political education, to do a good job in ideological cohesion and political guidance of young college students in the new era, and to improve the effectiveness of casting souls and educating people in universities in the new era, we must adhere to the guiding position of Marxism, take the all-round development of students as the center of the working thought, adhere to the education mode combining theory and practice as well as concise and lively expression technique.