Abstract: The results of the questionnaire survey on the cultivation of translation talents and the market demand show that traditional teaching methods, the ignorance of translation technology and the lack of necessary professional background are particularly prominent problems in the cultivation of translation talents. In view of the existing problems, this paper takes Anhui Province as an example and explores the "competence-centered" translation curriculum based on the theory of Developing A Curriculum (DACUM), so as to provide reference for the cultivation of translation talents in colleges and universities.