Abstract: To systematically summarize the overall characteristics and hot topics of enterprise digital transformation research since the COVID-19 epidemic, 194 articles on enterprise digital transformation from 2020 to 2022 in the WOS database were collected as samples. The VOSviewer bibliometric and visualization tool was utilized to identify the influential journals, authors, countries, research institutions and hot topics, and further draw knowledge structure maps for the latest research. The findings show that the latest global digital transformation research has focused on such hot topics as “digital transformation and firm innovation”, “digital transformation and organizational resilience”, “digital transformation and firm capabilities”, “digital transformation and sustainable development”, “digital transformation and new working styles”, and “digital transformation and crisis responsiveness for small and medium-sized enterprises”. Furthermore, there are close inherent logical relationships among these themes. Finally, future research directions are prospected focusing on the antecedents, outcomes, processes, and paths of enterprise digital transformation.